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Which part of the eye does a Coloboma affect?

  1. Optic Nerve

  2. Iris

  3. Sclera

  4. Cornea

The correct answer is: Iris

A coloboma primarily affects the iris, which is the colored part of the eye surrounding the pupil. This condition occurs as a result of incomplete closure of the embryonic fissure during the development of the eye. As a result, individuals with a coloboma of the iris may have a notch or gap in this structure, leading to distinctive features such as an irregular pupil shape. While colobomas can also affect other parts of the eye, such as the retina, choroid, or optic nerve, the iris is the most commonly recognized area impacted, making this option the most relevant in the context of the question. It's important to understand that a coloboma is an anatomical defect rather than a disease, and while it can have visual implications, its primary relationship in this case is with the structure of the iris.